New Entry
 |  | Name | Creator | Significance | Score |
|---|---|---|---|---|---|
| Eerie Cuties | Gisèle Lagacé | Major | 52 | |
| Effects and Side-Effects | Pheonix Dawn | Central | 32 | |
| El Goonish Shive | Dan Shive | Major | 96 | |
| El Hazard | Hiroki Hayashi | Minor | 4 | |
| Eva Parallel Reality Genesis | Lord the Night Knight | Minor | 4 | |
| Evil Genius | Catherine Jinks | Minor | 4 | ||
| Excel Saga | Watanabe Shin'ichi, Kōshi Rikudō | Minor | 4 | |
| Experimental | Darktayle | Central | 32 |