 | Dale | Chip 'n Dale: Rescue Rangers | 1 |
| Dan Granger | Harry Potter | 1 |
| Daniel Hillard | Mrs. Doubtfire | 1 |
| Daniel the Murderer | Chameleon Jail | 1 |
 | Danielle "Dani" Phantom | Danny Phantom | 1 |
| Daphne Blake | Scooby Doo | 1 |
| Dave | Sorority Boys | 1 |
| Dave Lister | Red Dwarf | 1 |
| Dave Skinner | The Joe Bates Saga | 1 |
| Dawn Summers | Buffy the Vampire Slayer | 1 |
| Dilton Doiley | Archie | 1 |
| Djinn | Gokudō-kun Man'yūki | 1 |
| Dominar Rygel XVI | Farscape | 1 |
| Don | The Sex Gates | 1 |
| Don Karnage | TaleSpin | 1 |
| Doofer | Sorority Boys | 1 |
| Doppelganger | Rosario+Vampire | 1 |
| Doris Trenton | Nancy Drew: The Mystery of the Brass Bound Trunk (1940) | 1 |
| Dr Henry Jekyll | Strange Case of Dr Jekyll and Mr Hyde | 1 |
| Dr. John A. Zoidberg | Futurama | 1 |
| Dr. John Hailey Watson | A Study in Magic | 1 |
| Dr. John Watson | Sherlock | 1 |
| Dr. Ono Tofu | Ranma ½ | 1 |
| Dr. Samuel Beckett | Quantum Leap | 1 |
| Dr. Sydney Catchadourian | Zerophilia | 1 |
| Draco Malfoy | Harry Potter | 6 |
| Dudley Dursley | Harry Potter | 1 |
| Dukey | Johnny Test | 1 |
| Duncan Cameron | The Eighth Weasley | 1 |
| Dylan Sanders | Charlie's Angels | 1 |
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